Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089840 | 0.86 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6090963 | 0.86 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6089697 | 0.85 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6088989 | 0.84 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6088826 | 0.83 | ALOX5 (0.49) | CYSLTR1CYSLTR2GPBAR1ALOX5SLC26A4 | |
| SCHEMBL5725146 | 0.83 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6087927 | 0.82 | MRGPRX4 (0.53) | MRGPRX4SLC26A4 | |
| SCHEMBL4450809 | 0.81 | NR4A2 (0.58) | MRGPRX4SLC26A4 | |
| SCHEMBL6091338 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL6091367 | 0.80 | FFAR1 (0.53) | MRGPRX4FFAR1SLC26A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |