Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450809 | 0.91 | NR4A2 (0.58) | MRGPRX4SLC26A4NR4A2PTGER4 | |
| SCHEMBL6089804 | 0.90 | FFAR1 (0.50) | FFAR1FFAR4MRGPRX4LTA4HPLA2G2A | |
| SCHEMBL6088674 | 0.86 | SLC26A4 (0.63) | FFAR1SLC26A4NR4A2PTGER4 | |
| SCHEMBL6087927 | 0.85 | MRGPRX4 (0.53) | MRGPRX4SLC26A4NR4A2 | |
| SCHEMBL6090965 | 0.85 | MRGPRX4 (0.60) | FFAR1FFAR4MRGPRX4 | |
| SCHEMBL6087956 | 0.84 | PTGER4 (0.55) | FFAR1FFAR4MRGPRX4SLC26A4NR4A2 | |
| SCHEMBL6088820 | 0.84 | FFAR1 (0.55) | FFAR1FFAR4MRGPRX4NR4A2LTA4H | |
| SCHEMBL6092100 | 0.82 | RXRA (0.51) | MRGPRX4SLC26A4NR4A2PTGER4 | |
| SCHEMBL6088680 | 0.81 | NR4A2 (0.62) | MRGPRX4SLC26A4NR4A2 | |
| SCHEMBL6091862 | 0.81 | SLC26A4 (0.52) | FFAR1FFAR4SLC26A4NR4A2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |