Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092667 | 0.81 | PTGDR2 (0.37) | CYSLTR1GPBAR1PTGDR2CYSLTR2CYP1A2 | |
| SCHEMBL6089639 | 0.77 | CYSLTR1 (0.41) | CYSLTR1GPBAR1SIRT2PTGDR2CYSLTR2 | |
| SCHEMBL6089338 | 0.69 | CYP1A2 (0.37) | CYSLTR1GPBAR1SIRT2CYSLTR2CYP1A2 | |
| SCHEMBL6090578 | 0.67 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2CYP1A2ALOX5 | |
| SCHEMBL6089645 | 0.66 | CYSLTR1 (0.39) | CYSLTR1GPBAR1CYSLTR2CYP1A2ALOX5 | |
| SCHEMBL3875985 | 0.65 | MLKL (0.48) | — | |
| SCHEMBL6089838 | 0.65 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2CYP1A2ALOX5 | |
| SCHEMBL6092671 | 0.65 | CYSLTR1 (0.39) | CYSLTR1GPBAR1PTGDR2CYSLTR2CYP1A2 | |
| SCHEMBL6088426 | 0.65 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| SCHEMBL5725146 | 0.64 | CYSLTR1 (0.67) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |