Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088820 | 0.87 | FFAR1 (0.55) | MRGPRX4PTGDR2FFAR1PPARDPTGER1 | |
| SCHEMBL6092051 | 0.86 | FFAR1 (0.51) | MRGPRX4PTGDR2FFAR1MAOB | |
| SCHEMBL6090373 | 0.85 | MRGPRX4 (0.59) | MRGPRX4PTGDR2FFAR1PPARDPPARA | |
| SCHEMBL6092205 | 0.85 | PTGDR2 (0.53) | PTGDR2FFAR1PPARDPTGER1PTGER4 | |
| SCHEMBL6087927 | 0.84 | MRGPRX4 (0.53) | MRGPRX4PTGER3MAOB | |
| SCHEMBL6090698 | 0.83 | NR4A2 (0.61) | MRGPRX4PTGDR2FFAR1PPARDPTGER1 | |
| SCHEMBL6091148 | 0.83 | PTGDR2 (0.47) | MRGPRX4PTGDR2FFAR1PPARDPTGER1 | |
| SCHEMBL6089372 | 0.83 | CYSLTR1 (0.62) | — | |
| SCHEMBL6090183 | 0.82 | PTGER1 (0.50) | PTGDR2FFAR1PPARDPTGER1PTGER4 | |
| SCHEMBL6088282 | 0.82 | ALOX5 (0.42) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |