Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091148 | 0.84 | PTGDR2 (0.47) | NR4A2PPARDPPARAPTGDR2FFAR1 | |
| SCHEMBL6091321 | 0.84 | NR4A2 (0.66) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL6089768 | 0.83 | MRGPRX4 (0.49) | PPARDPPARAPTGDR2MAOBFFAR1 | |
| SCHEMBL6092051 | 0.83 | FFAR1 (0.51) | NR4A2RXRARXRBPTGDR2MAOB | |
| SCHEMBL6090373 | 0.82 | MRGPRX4 (0.59) | SMN1; SMN2PPARDPPARAPTGDR2MAOB | |
| SCHEMBL6092205 | 0.82 | PTGDR2 (0.53) | NR4A2PPARDPPARAPTGDR2MAOB | |
| SCHEMBL6088820 | 0.81 | FFAR1 (0.55) | NR4A2PPARDPTGDR2FFAR1PTGER2 | |
| SCHEMBL6087649 | 0.81 | NR4A2 (0.53) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL6088578 | 0.80 | NR4A2 (0.57) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL6088801 | 0.80 | GPR132 (0.51) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |