Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092205 | 0.90 | PTGDR2 (0.53) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL6088820 | 0.84 | FFAR1 (0.55) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL6090373 | 0.83 | MRGPRX4 (0.59) | PTGDR2PPARAFFAR1PPARDLMNA | |
| SCHEMBL6088500 | 0.83 | PTGDR2 (0.46) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL6089768 | 0.82 | MRGPRX4 (0.49) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL6090892 | 0.82 | BCHE (0.40) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL6088697 | 0.82 | PTGDR2 (0.46) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL6091148 | 0.81 | PTGDR2 (0.47) | PTGER1PTGER4PTGER3PTGER2PTGDR2 | |
| SCHEMBL6088801 | 0.81 | GPR132 (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6089340 | 0.80 | PTGDR2 (0.48) | PTGER1PTGER4PTGER3PTGER2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |