Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089866 | 1.00 | KDR (0.34) | KDRRETALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6088538 | 0.82 | KDR (0.33) | KDRRET | |
| SCHEMBL6088541 | 0.82 | KDR (0.33) | KDRRET | |
| SCHEMBL6091333 | 0.81 | RET (0.37) | KDRRETALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6091336 | 0.81 | RET (0.37) | KDRRETALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6089792 | 0.80 | RET (0.53) | KDRRETALDH1A1L3MBTL1RPS6KA3 | |
| SCHEMBL6089797 | 0.80 | RET (0.53) | KDRRETALDH1A1L3MBTL1RPS6KA3 | |
| SCHEMBL6088928 | 0.77 | SIRT1 (0.45) | KDRRETMAPT | |
| SCHEMBL6088932 | 0.77 | SIRT1 (0.45) | KDRRETMAPT | |
| SCHEMBL6088131 | 0.76 | RET (0.37) | KDRRETALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |