Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088329 | 0.90 | MAOB (0.52) | NR4A2NPC1RAB9AMAOBSLC26A4 | |
| SCHEMBL6088771 | 0.89 | NR4A2 (0.58) | NR4A2NPC1RAB9AMEN1SLC26A4 | |
| SCHEMBL6089332 | 0.87 | NR4A2 (0.67) | NR4A2NPC1RAB9AMAOBMAOA | |
| SCHEMBL6088473 | 0.86 | HIF1A (0.57) | NR4A2MAOBKMT2ALMNASMN1; SMN2 | |
| SCHEMBL6087974 | 0.85 | HIF1A (0.58) | NR4A2NPC1RAB9AMAOBMAOA | |
| SCHEMBL6088324 | 0.85 | MAOB (0.45) | MAOBMEN1SLC26A4KMT2ALMNA | |
| SCHEMBL6088781 | 0.85 | MAOB (0.44) | NR4A2NPC1RAB9AMAOBSLC26A4 | |
| SCHEMBL5724594 | 0.84 | HIF1A (0.53) | NPC1RAB9AMAOBSLC26A4LMNA | |
| SCHEMBL6088841 | 0.82 | MAPT (0.50) | NPC1RAB9AMAOBSLC26A4KMT2A | |
| SCHEMBL6088959 | 0.82 | MAOB (0.48) | NPC1RAB9AMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |