Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092648 | 0.89 | KDM4E (0.47) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL5731708 | 0.88 | ALDH1A1 (0.50) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL5731755 | 0.88 | KDM4E (0.48) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL6092472 | 0.80 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL5731692 | 0.80 | ALDH1A1 (0.42) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL21776525 | 0.75 | SMN1; SMN2 (0.41) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL6089942 | 0.74 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL22730883 | 0.70 | ALDH1A1 (0.60) | KDM4EMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL6493537 | 0.70 | HMGCR (0.45) | HMGCR | |
| SCHEMBL10418649 | 0.70 | ALDH1A1 (0.47) | KDM4EMEN1ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006059210-A2 | FUSED BICYCLIC PYRROLS AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-08 | — | — | WO | disclosed |