Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616823 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL698093 | 0.82 | LMNA (0.35) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL2020959 | 0.81 | TDP1 (0.58) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL29497534 | 0.81 | TDP1 (0.58) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL10415657 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL4157946 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1TDP1LMNAHTT | |
| Hydrochloric Acid SCHEMBL2016801 | 0.79 | TDP1 (0.56) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL3627129 | 0.78 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL15068206 | 0.78 | KCNK2 (0.43) | KDM4EALDH1A1TDP1LMNAHTT | |
| SCHEMBL998647 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1TDP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601235-B1 | BICYCLIC HETEROARYL DERIVATIVES, PREPARATION AND THERAPEUTIC USES THEREOF | XWPHARMA LTD (KY) | 2026-03-04 | — | — | EP | disclosed |
| CN-113811532-B | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116888101-A | Substituted isoxazoline derivatives | 巴斯夫欧洲公司 | 2023-10-13 | — | — | CN | disclosed |
| US-11639337-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XWPharma Ltd. (KY) | 2023-05-02 | — | — | US | disclosed |
| US-20220298127-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | XWPharma Ltd. (KY) | 2022-09-22 | — | — | US | disclosed |
| CN-115025086-A | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-11401249-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XWPharma Ltd. (KY) | 2022-08-02 | — | — | US | disclosed |
| US-20220217979-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-07-14 | — | — | US | disclosed |
| CN-110709386-B | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-20220132850-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-05 | — | — | US | disclosed |
| US-20210094925-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | XWPharma Ltd. (KY) | 2021-04-01 | — | — | US | disclosed |
| US-10882832-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XW LABORATORIES INC. (KY) | 2021-01-05 | — | — | US | disclosed |
| WO-2020203763-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-20200181102-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | XWPharma Ltd. (KY) | 2020-06-11 | — | — | US | disclosed |
| US-10640476-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XW LABORATORIES INC. (KY) | 2020-05-05 | — | — | US | disclosed |
| CN-101570494-B | N-phenyl-dichloroacetamide and derivatives as well as preparation method and application thereof | UNIV TSINGHUA | 2013-04-03 | — | — | CN | disclosed |
| CN-101570494-A | N-phenyl-dichloroacetamide and derivatives as well as preparation method and application thereof | UNIV TSINGHUA (CN) | 2009-11-04 | — | — | CN | disclosed |
| WO-2006099957-A1 | INSECTICIDAL AND ACARICIDAL ANILINOTRIAZOLES | BAYER CROPSCIENCE AG (DE) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298127-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-10882832-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-11401249-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-20200181102-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-10640476-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-11639337-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-20220217979-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | C5, COX6C, C1S | KDM4E 1825/4885ALDH1A1 1268/4885TDP1 4362/4885 |
| US-20210094925-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | GRIN2A, GRIN2C, GRIN3A | KDM4E 2619/4885ALDH1A1 742/4885TDP1 2034/4885 |
| US-20220132850-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, AADAC, ACHE | KDM4E 2168/4885ALDH1A1 127/4885TDP1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.