Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EIF2S1 | P05198 | 2/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | STK16 | O75716 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372973 | 0.83 | NPC1 (0.50) | KDRAURKAAURKBNPC1RAB9A | |
| SCHEMBL4372131 | 0.78 | ALDH1A1 (0.47) | PDE10ASMN1; SMN2MAPTLMNAEIF2S1 | |
| SCHEMBL6092695 | 0.77 | PDE10A (0.44) | PDE10ANPC1RAB9AATMSMN1; SMN2 | |
| SCHEMBL6092359 | 0.77 | ALDH1A1 (0.46) | PDE10ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6090851 | 0.72 | MAPT (0.50) | ARNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4372536 | 0.72 | MAPT (0.50) | ARNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4377654 | 0.72 | ANO1 (0.48) | PDE10A | |
| SCHEMBL6091957 | 0.70 | LMNA (0.54) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL6092966 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTLMNA | |
| SCHEMBL6094816 | 0.70 | LMNA (0.54) | NPC1RAB9ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2006-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | AR, SHBG, BRCA1 | AR 1/4885PDE10A 2439/4885KDR 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.