Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089586 | 0.88 | GFER (0.33) | — | |
| SCHEMBL6089582 | 0.88 | GFER (0.33) | — | |
| SCHEMBL6092889 | 0.88 | KDR (0.34) | DAOGPR84 | |
| SCHEMBL6090018 | 0.83 | GPR84 (0.34) | ESR1ESR2DAOPDPK1GPR84 | |
| SCHEMBL6090013 | 0.83 | GPR84 (0.34) | ESR1ESR2DAOPDPK1GPR84 | |
| SCHEMBL6089530 | 0.81 | PDPK1 (0.34) | ESR1ESR2DAOPDPK1NR1H3 | |
| SCHEMBL6089536 | 0.81 | PDPK1 (0.34) | ESR1ESR2DAOPDPK1NR1H3 | |
| SCHEMBL6090443 | 0.80 | PDPK1 (0.45) | PDPK1 | |
| SCHEMBL6091571 | 0.77 | SIRT1 (0.42) | DAOEGFRGPR84 | |
| SCHEMBL6090145 | 0.77 | PDPK1 (0.34) | ESR1ESR2PDPK1EGFRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |