Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089942 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL5730486 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL5732191 | 0.87 | PRKCZ (0.49) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL15497074 | 0.81 | POLB (0.46) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL5731877 | 0.78 | PRKCZ (0.47) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL5731315 | 0.77 | HSD17B10 (0.44) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL16828410 | 0.74 | PRKCZ (0.51) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8601174 | 0.74 | SLC6A4 (0.69) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL31619940 | 0.73 | PRKCZ (0.56) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL6092648 | 0.73 | KDM4E (0.47) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006059210-A2 | FUSED BICYCLIC PYRROLS AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-08 | — | — | WO | disclosed |