Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | EDNRB | P24530 | 3/20 | 0.48 |
| ▸ | EDNRA | P25101 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092403 | 0.81 | MAPT (0.41) | MAPTMEN1KMT2ALMNAEDNRB | |
| SCHEMBL6091749 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6092119 | 0.76 | MAPT (0.42) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7477872 | 0.74 | MRGPRX4 (0.74) | RAB9ANR4A2MRGPRX4NR1H4 | |
| SCHEMBL5745661 | 0.74 | PPARG (0.54) | EDNRBEDNRASERPINE1 | |
| SCHEMBL12533265 | 0.73 | MAOB (0.66) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2808240 | 0.73 | SERPINE1 (0.57) | EDNRBEDNRANR4A2SERPINE1 | |
| SCHEMBL8545345 | 0.72 | EDNRB (0.69) | EDNRBEDNRASERPINE1 | |
| SCHEMBL8856902 | 0.72 | EDNRB (0.58) | MEN1KMT2ALMNAEDNRBEDNRA | |
| SCHEMBL8991408 | 0.71 | MAOB (0.79) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | MAPT 3503/4885MEN1 3878/4885KMT2A 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.