Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091691 | 0.88 | TP53 (0.44) | TP53GSK3BTHRBPTGESYWHAH | |
| SCHEMBL6091172 | 0.88 | TP53 (0.41) | TP53GSK3BTHRBPPARGPTGES | |
| SCHEMBL6090090 | 0.87 | PPARG (0.41) | TP53PLA2G1BHTTL3MBTL1ATG4B | |
| SCHEMBL5747009 | 0.87 | THRB (0.45) | TP53GSK3BTHRBPPARG | |
| SCHEMBL5739167 | 0.83 | PTGES (0.46) | PLA2G1BHTTL3MBTL1ATG4BPTGES | |
| SCHEMBL6089685 | 0.82 | GRIN1 (0.44) | TP53GSK3BTHRBPTGES | |
| SCHEMBL6089609 | 0.80 | PTGES (0.42) | TP53GSK3BTHRBPTGES | |
| SCHEMBL6091802 | 0.78 | PTGES (0.50) | TP53PPARGPTGESYWHAH | |
| SCHEMBL6091726 | 0.77 | YWHAH (0.41) | TP53PPARGPTGESYWHAH | |
| SCHEMBL6090079 | 0.77 | TP53 (0.42) | TP53PPARGPTGESYWHAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | TP53 2032/4885GSK3B 1452/4885THRB 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.