Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191425 | 0.83 | KMT2A (0.60) | KMT2ATSHRMEN1ALDH1A1NPC1 | |
| SCHEMBL7144056 | 0.77 | KMT2A (0.62) | KMT2APKMTSHRSMN1; SMN2MEN1 | |
| SCHEMBL21154355 | 0.76 | CALM1 (0.54) | KMT2AMEN1VKORC1TAAR1CYP3A4 | |
| SCHEMBL6724285 | 0.76 | CYP3A4 (0.51) | KMT2APKMTSHRSMN1; SMN2TAAR1 | |
| SCHEMBL9672470 | 0.76 | TAAR1 (0.53) | KMT2APKMTSHRSMN1; SMN2TAAR1 | |
| SCHEMBL109195 | 0.76 | TAAR1 (0.64) | CMA1TAAR1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL28766778 | 0.75 | MIF (0.55) | KMT2APKMTSHRSMN1; SMN2MEN1 | |
| SCHEMBL1422874 | 0.75 | ALDH1A1 (0.58) | TAAR1CYP1A2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL108109 | 0.74 | TAAR1 (0.62) | CMA1TAAR1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9391810 | 0.74 | CYP1A2 (0.49) | KMT2AMEN1TAAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009062-B2 | Process for the preparation of flavone derivatives | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | disclosed |