SCHEMBL6093250

SCHEMBL6093250

c1ccc(/N=N/N2CCCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.61
GAA P10253 2/20 0.61
RAB9A P51151 8/20 0.59
NPC1 O15118 7/20 0.59
SMN1; SMN2 Q16637 5/20 0.59
HTT P42858 3/20 0.59
ALDH1A1 P00352 2/20 0.59
CYP1A1 P04798 2/20 0.44
CYP1B1 Q16678 2/20 0.44
KMT2A Q03164 3/20 0.42
LMNA P02545 1/20 0.42
MEN1 O00255 2/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6093254 1.00 MAPT (0.61) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL17375296 0.98 RAB9A (0.62) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL22390775 0.98 RAB9A (0.62) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL17375298 0.98 RAB9A (0.62) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL22390777 0.98 RAB9A (0.62) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL13591514 0.83 NPC1 (0.57) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL14709063 0.83 SIGMAR1 (0.47) MAPTGAARAB9ANPC1SMN1; SMN2
Piperazine SCHEMBL28234534 0.81 SIGMAR1 (0.45) MAPTGAARAB9ANPC1SMN1; SMN2
Iodide SCHEMBL27408 0.80 RAB9A (0.54) MAPTGAARAB9ANPC1SMN1; SMN2
SCHEMBL17375252 0.78 MAPT (0.58) MAPTGAARAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254284-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2024-08-01 US claimed
US-20200283580-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 US claimed
US-12180385-B2 Shelf life stable and improved mass polymerizable polycyclic-olefinic compositions PROMERYS, LLC (US) 2024-12-31 US disclosed
US-20240254284-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2024-08-01 US disclosed
US-11845880-B2 Polycyclic-olefinic compositions for low-loss films having improved thermal properties PROMERUS, LLC (US) 2023-12-19 US disclosed
US-20220135832-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS PROMERUS, LLC (US) 2022-05-05 US disclosed
US-20220135831-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 US disclosed
US-20200283580-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 US disclosed
WO-2006055951-A2 TETRAHYDROISOQUINOLINES AS FACTOR XA INHIBITORS PORTOLA PHARMACEUTICALS, INC. (US) 2006-05-26 WO disclosed