Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771789 | 0.89 | ENPP2 (0.46) | PELI1ENPP2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6098470 | 0.86 | PELI1 (0.49) | PELI1SMN1; SMN2ALDH1A1HPGDTRPV1 | |
| Hydrochloric Acid SCHEMBL6094972 | 0.85 | PELI1 (0.48) | PELI1SMN1; SMN2ALDH1A1HPGDTRPV1 | |
| SCHEMBL6094563 | 0.85 | PELI1 (0.62) | PELI1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6095855 | 0.83 | PELI1 (0.61) | PELI1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6138775 | 0.83 | SMN1; SMN2 (0.40) | ENPP2SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6096102 | 0.81 | PELI1 (0.47) | PELI1ENPP2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6095866 | 0.76 | PELI1 (0.40) | PELI1ENPP2SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6095870 | 0.76 | PELI1 (0.40) | PELI1ENPP2SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL6094793 | 0.76 | TRPV1 (0.57) | PELI1SMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | PELI1 1293/4885ENPP2 4395/4885SMN1; SMN2 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.