Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138775 | 0.94 | SMN1; SMN2 (0.40) | ENPP2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6096102 | 0.89 | PELI1 (0.47) | ENPP2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6093385 | 0.89 | PELI1 (0.47) | ENPP2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6770831 | 0.86 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6139110 | 0.84 | HPGD (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6096742 | 0.76 | PELI1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6771360 | 0.76 | MAPK1 (0.40) | ENPP2ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL6771363 | 0.76 | MAPK1 (0.40) | ENPP2ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL6772609 | 0.76 | RAB9A (0.54) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6777099 | 0.75 | ENPP2 (0.46) | ENPP2POLBL3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | ENPP2 2560/4885ALDH1A1 31/4885SMN1; SMN2 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.