Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.50 |
| ▸ | ITGAL | P20701 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6093514 | 0.99 | TRPV1 (0.56) | TRPV1RAB9ANPC1KDM4EHPGD | |
| SCHEMBL6772609 | 0.88 | RAB9A (0.54) | TRPV1RAB9ANPC1KDM4EHPGD | |
| SCHEMBL6094563 | 0.87 | PELI1 (0.62) | TRPV1RAB9ANPC1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6095855 | 0.86 | PELI1 (0.61) | TRPV1RAB9ANPC1KDM4EHPGD | |
| SCHEMBL6093756 | 0.84 | POLB (0.52) | TRPV1RAB9AKDM4EHPGDITGB2 | |
| SCHEMBL6098470 | 0.84 | PELI1 (0.49) | TRPV1HPGDL3MBTL1PELI1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6094577 | 0.83 | ALDH1A1 (0.52) | TRPV1RAB9AKDM4EHPGDITGB2 | |
| Hydrochloric Acid SCHEMBL6094972 | 0.83 | PELI1 (0.48) | TRPV1HPGDL3MBTL1PELI1ALDH1A1 | |
| SCHEMBL6096644 | 0.78 | RAB9A (0.52) | TRPV1RAB9ANPC1KDM4EHPGD | |
| SCHEMBL7572404 | 0.76 | RAB9A (0.67) | RAB9ANPC1KDM4EHPGDITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | TRPV1 873/4885RAB9A 4080/4885NPC1 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.