SCHEMBL6094079

SCHEMBL6094079

NS(=O)(=O)c1nc2c(S)cccc2s1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.56
CA1 P00915 9/20 0.56
CA4 P22748 5/20 0.56
CA12 O43570 4/20 0.56
CA14 Q9ULX7 3/20 0.56
CA7 P43166 3/20 0.56
CA5A P35218 3/20 0.43
CA9 Q16790 3/20 0.43
CA6 P23280 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CA3 P07451 1/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38
HIF1A Q16665 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PDPK1 O15530 1/20 0.38
PSMB8 P28062 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28135377 0.83 PSMB8 (0.38) CA2CA1CA4CA12CA14
SCHEMBL10347933 0.81 CA2 (0.57) CA2CA1CA4CA12CA14
SCHEMBL1038694 0.81 PDPK1 (0.59) CA2CA1CA4CA12CA14
SCHEMBL28261262 0.78 CA2 (0.53) CA2CA1CA4CA12CA14
SCHEMBL8522568 0.76 CA2 (0.51) CA2CA1CA4CA12CA14
SCHEMBL4364308 0.73 ALDH1A1 (0.61) LMNAPKMKMT2ATDP1PDPK1
SCHEMBL5329551 0.73 CA2 (0.51) CA2CA1CA4CA12CA14
SCHEMBL540891 0.73 CA2 (0.48) CA2CA1CA4CA12CA14
SCHEMBL8898795 0.72 PSMD14 (0.36) KDM4ELMNAPKMKMT2ATDP1
SCHEMBL3067465 0.72 PSMD14 (0.42) KDM4ELMNAPKMKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084212-B2 Vulcanization accelerators GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) 2006-08-01 US claimed