Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094401 | 1.00 | OXTR (0.46) | OXTRPSMB9L3MBTL1HTR1AHTR1B | |
| SCHEMBL7083700 | 0.83 | OXTR (0.69) | OXTRL3MBTL1HTR1AHTR1BHTR2A | |
| SCHEMBL4942988 | 0.79 | OXTR (0.71) | OXTRHTR1AHTR1BHTR2AHTR2C | |
| SCHEMBL5481224 | 0.78 | HPGD (0.46) | OXTRPOLBLMNAPKMALDH1A1 | |
| SCHEMBL301777 | 0.70 | OXTR (0.51) | OXTRAVPR1APOLBLMNAALDH1A1 | |
| SCHEMBL8320159 | 0.70 | HPGD (0.44) | OXTRAVPR1APOLBLMNAALDH1A1 | |
| SCHEMBL4419397 | 0.70 | HPGD (0.44) | OXTRAVPR1APOLBLMNAALDH1A1 | |
| SCHEMBL4417850 | 0.70 | OXTR (0.51) | OXTRAVPR1APOLBLMNAALDH1A1 | |
| SCHEMBL4418365 | 0.69 | HPGD (0.43) | OXTRAVPR1APOLBLMNAALDH1A1 | |
| SCHEMBL4418361 | 0.69 | HPGD (0.43) | OXTRAVPR1APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018988-B2 | Pharmaceutically active pyrrolidine derivatives as Bax inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-03-28 | — | — | US | disclosed |