Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.51 |
| ▸ | ITGAL | P20701 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094793 | 0.88 | TRPV1 (0.57) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6096644 | 0.88 | RAB9A (0.52) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6139110 | 0.87 | HPGD (0.49) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6093514 | 0.86 | TRPV1 (0.56) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6770831 | 0.83 | SMN1; SMN2 (0.44) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL7572404 | 0.83 | RAB9A (0.67) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL7572398 | 0.83 | RAB9A (0.67) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6138775 | 0.78 | SMN1; SMN2 (0.40) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL9656533 | 0.77 | TRPV1 (0.64) | RAB9ANPC1KDM4EHPGDL3MBTL1 | |
| SCHEMBL9656530 | 0.77 | TRPV1 (0.64) | RAB9ANPC1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | RAB9A 4670/4885NPC1 4808/4885KDM4E 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.