Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.78 |
| ▸ | AR | P10275 | 11/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.77 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | RAF1 | P04049 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094870 | 0.92 | CYP3A4 (0.85) | CYP3A4MAPTPOLHARMEN1 | |
| SCHEMBL7033517 | 0.92 | CYP3A4 (0.84) | CYP3A4MAPTPOLHARMEN1 | |
| SCHEMBL30335147 | 0.88 | POLH (1.00) | CYP3A4MAPTPOLHARMEN1 | |
| SCHEMBL31291006 | 0.88 | POLH (1.00) | CYP3A4MAPTPOLHARMEN1 | |
| 5-Hydroxyflavone SCHEMBL158303 | 0.87 | AR (1.00) | CYP3A4MAPTPOLHARMEN1 | |
| 5-Hydroxyflavone SCHEMBL2390993 | 0.87 | AR (1.00) | CYP3A4MAPTPOLHARMEN1 | |
| 5-Hydroxyflavone SCHEMBL30630415 | 0.87 | AR (1.00) | CYP3A4MAPTPOLHARMEN1 | |
| 5-Hydroxyflavone SCHEMBL2390943 | 0.86 | AR (0.97) | CYP3A4MAPTPOLHARMEN1 | |
| SCHEMBL157490 | 0.86 | AR (1.00) | CYP3A4MAPTPOLHARMEN1 | |
| 5-Hydroxyflavone SCHEMBL28317755 | 0.86 | AR (0.97) | CYP3A4MAPTPOLHARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155501-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT CANCERS | WAYNE STATE UNIVERSITY (US) | 2020-05-21 | — | — | US | claimed |
| WO-2019005829-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT CANCERS | WAYNE STATE UNIVERSITY (US) | 2019-01-03 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-20260014137-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | WAYNE STATE UNIVERSITY (US) | 2026-01-15 | — | — | US | disclosed |
| US-12458636-B2 | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders | WAYNE STATE UNIVERSITY (US) | 2025-11-04 | — | — | US | disclosed |
| US-20240245672-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | UNITED STATES GOVERNMENT | 2024-07-25 | — | — | US | disclosed |
| US-11938127-B2 | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders | WAYNE STATE UNIVERSITY (US) | 2024-03-26 | — | — | US | disclosed |
| EP-4258900-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONOIDS AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| US-20230102174-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | UNITED STATES GOVERNMENT | 2023-03-30 | — | — | US | disclosed |
| US-20230102174-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | UNITED STATES GOVERNMENT | 2023-03-30 | — | — | US | disclosed |
| US-20070265317-A1 | MODIFIED CHALCONE COMPOUNDS AS ANTIMITOTIC AGENTS | ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | CYP3A4 17/4885MAPT 4566/4885POLH 4592/4885 |
| US-20070265317-A1 | MODIFIED CHALCONE COMPOUNDS AS ANTIMITOTIC AGENTS | TUBA1C, SARS1, TUBB1 | CYP3A4 2182/4885MAPT 400/4885POLH 1424/4885 |
| US-12458636-B2 | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders | CYP21A2, NR3C2, NR5A1 | CYP3A4 435/4885MAPT 4813/4885POLH 955/4885 |
| US-20230102174-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | CYP21A2, MC2R, GHRHR | CYP3A4 511/4885MAPT 4851/4885POLH 1108/4885 |
| US-20240245672-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | CYP21A2, NR3C2, NR5A1 | CYP3A4 435/4885MAPT 4813/4885POLH 955/4885 |
| US-11938127-B2 | Methods and compositions relating to steroid hormone receptor-dependent proliferative disorders | CYP21A2, MC2R, GHRHR | CYP3A4 511/4885MAPT 4851/4885POLH 1108/4885 |
| US-20260014137-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT PROLIFERATIVE DISORDERS | CYP21A2, NR3C2, HSD3B2 | CYP3A4 296/4885MAPT 4842/4885POLH 1254/4885 |
| US-20200155501-A1 | METHODS AND COMPOSITIONS RELATING TO STEROID HORMONE RECEPTOR-DEPENDENT CANCERS | ESRRA, ESRRB, NR3C1 | CYP3A4 4448/4885MAPT 4474/4885POLH 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.