Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609648 | 0.91 | GPR119 (0.43) | PDE4BGPR119CHRM2 | |
| SCHEMBL608827 | 0.87 | PDE4B (0.40) | PDE4BGPR119HSD11B1PIK3CD | |
| SCHEMBL10058398 | 0.86 | PDE4B (0.39) | PDE4BGPR119HSD11B1PIK3CDOPRK1 | |
| SCHEMBL612615 | 0.81 | PDE4B (0.37) | PDE4BGPR119HSD11B1PIK3CD | |
| SCHEMBL609219 | 0.78 | PDE4B (0.39) | PDE4BGPR119HSD11B1PIK3CD | |
| SCHEMBL609218 | 0.78 | PDE4B (0.39) | PDE4BGPR119HSD11B1PIK3CD | |
| SCHEMBL10058391 | 0.77 | GPR119 (0.40) | PDE4BGPR119CHRM2 | |
| SCHEMBL611813 | 0.77 | GPR119 (0.41) | PDE4BGPR119 | |
| SCHEMBL13186587 | 0.75 | GPR119 (0.42) | PDE4BGPR119 | |
| SCHEMBL2181628 | 0.74 | GPR119 (0.44) | PDE4BGPR119CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, GPR132, FFAR2 | PDE4B 451/4885GPR119 1/4885HSD11B1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.