Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CBX7 | O95931 | 1/20 | 0.45 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.45 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096108 | 0.89 | L3MBTL1 (0.72) | L3MBTL1ALDH1A1SMPD1CMA1BRD4 | |
| SCHEMBL15176632 | 0.86 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1SMPD1CMA1BRD4 | |
| SCHEMBL16794826 | 0.85 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1SMPD1CMA1CBX7 | |
| SCHEMBL16814286 | 0.83 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1SMPD1CMA1BRD4 | |
| SCHEMBL8554715 | 0.83 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1SMPD1CMA1CBX7 | |
| SCHEMBL29790735 | 0.82 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL18581323 | 0.82 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL6098970 | 0.82 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1SMPD1CMA1BRD4 | |
| SCHEMBL13973607 | 0.81 | L3MBTL1 (0.44) | L3MBTL1BRD4MEN1KMT2AMAPT | |
| SCHEMBL15874599 | 0.80 | L3MBTL1 (0.72) | L3MBTL1ALDH1A1SMPD1CMA1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101876-B2 | Substituted benzoxazines as integrin antagonists | PHARMACIA CORPORATION (US) | 2006-09-05 | — | — | US | disclosed |
| US-20040224948-A1 | Novel substituted benzoxazines as integrin antagonists | PHARMACIA & UPJOHN S.P.A. (IT) | 2004-11-11 | — | — | US | disclosed |
| US-6750215-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-06-15 | — | — | US | disclosed |
| US-20030073688-A1 | Novel substituted benzoxazines as integrin antagonists | POLSTER, RACHEL A. | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224948-A1 | Novel substituted benzoxazines as integrin antagonists | ITGB1, ITGA1, ITGB3 | L3MBTL1 4235/4885ALDH1A1 620/4885SMPD1 946/4885 |
| US-20030073688-A1 | Novel substituted benzoxazines as integrin antagonists | ITGB1, ITGA1, ITGB3 | L3MBTL1 4235/4885ALDH1A1 620/4885SMPD1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.