Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094016 | 0.82 | ROCK2 (0.52) | PTPN7HTTKDM4ERAB9AKDR | |
| SCHEMBL4367821 | 0.80 | EPHX1 (0.48) | EPHX1PTPN7SMN1; SMN2CDK8ALDH1A1 | |
| SCHEMBL20707804 | 0.79 | ADORA2A (0.46) | SMN1; SMN2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6091476 | 0.79 | KMT2A (0.46) | SMN1; SMN2CDK8KMT2AKDM4EMEN1 | |
| SCHEMBL4371236 | 0.79 | ROCK2 (0.47) | SMN1; SMN2MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6092098 | 0.78 | HSD17B10 (0.46) | SMN1; SMN2MAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL4365497 | 0.74 | MAPT (0.45) | SMN1; SMN2HTTMAPTKMT2AALDH1A1 | |
| SCHEMBL4372959 | 0.74 | KDM4E (0.44) | SMN1; SMN2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL4372770 | 0.74 | KDR (0.55) | SMN1; SMN2MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6092660 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036098-A1 | Carbonylamino-benzimidazole derivatives as androgen receptor modulators | AR, SHBG, BRCA1 | EPHX1 3780/4885PTPN7 4485/4885SMN1; SMN2 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.