Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 10/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 9/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.55 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 2/20 | 0.49 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MYLK | Q15746 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095885 | 0.89 | TMPRSS4 (0.50) | TMPRSS4P2RX1P2RX4P2RX7PLG | |
| SCHEMBL6094625 | 0.86 | KCNMA1 (0.52) | PLGKLK1KLK6KLKB1SMN1; SMN2 | |
| SCHEMBL6096885 | 0.85 | PPARA (0.48) | PPARASMN1; SMN2NPC1GMNNLMNA | |
| SCHEMBL6096677 | 0.81 | P2RX1 (0.58) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL6097354 | 0.79 | P2RX1 (0.53) | TMPRSS4P2RX1P2RX4P2RX7SMN1; SMN2 | |
| SCHEMBL23388966 | 0.78 | TMPRSS4 (0.63) | TMPRSS4P2RX1P2RX4P2RX7PLG | |
| SCHEMBL6097223 | 0.77 | P2RX1 (0.47) | P2RX1PLGKLK1KLK6KLKB1 | |
| SCHEMBL6095574 | 0.77 | P2RX1 (0.45) | TMPRSS4P2RX1PLGKLK1KLK6 | |
| SCHEMBL24460414 | 0.76 | P2RX1 (0.80) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL6096112 | 0.76 | PPARA (0.50) | PPARALMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064124-B2 | NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-06-20 | — | — | US | claimed |
| US-7064124-B2 | NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-06-20 | — | — | US | disclosed |
| US-20040122244-A1 | Nf-kappa b inhibitor containing substituted benzoic acid derivative as active ingredient | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2004-06-24 | — | — | US | disclosed |
| EP-1314712-A1 | NF-KAPPA-B INHIBITOR CONTAINING SUBSTITUTED BENZOIC ACID DERIVATIVE AS ACTIVE INGREDIENT | Daiichi Suntory Pharma Co., Ltd. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122244-A1 | Nf-kappa b inhibitor containing substituted benzoic acid derivative as active ingredient | NFKBIA, NFKB1, IKBKB | TMPRSS4 3293/4885P2RX1 4484/4885P2RX4 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.