Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097336 | 0.91 | HTT (0.50) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL6097122 | 0.90 | AR (0.44) | ALDH1A1ARKMT2ALMNACYP2C9 | |
| SCHEMBL6097463 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1ARMEN1KMT2AGAA | |
| SCHEMBL6095919 | 0.90 | AR (0.45) | ALDH1A1ARLMNACYP2C9HPGD | |
| SCHEMBL6095079 | 0.84 | AR (0.43) | ALDH1A1ARGAALMNACYP2C9 | |
| SCHEMBL6096236 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ARMEN1KMT2AGAA | |
| SCHEMBL6077777 | 0.83 | AR (0.56) | ALDH1A1ARMEN1KMT2AGAA | |
| SCHEMBL6110711 | 0.82 | AR (0.46) | AR | |
| SCHEMBL6094713 | 0.81 | QPCT (0.42) | ALDH1A1ARMEN1KMT2AGAA | |
| SCHEMBL6095932 | 0.81 | ALOX12 (0.47) | ALDH1A1ARMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115745-B2 | Benzyl urea and thiourea derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-10-03 | — | — | US | claimed |
| EP-1597233-A1 | BENZYL UREA AND THIOUREA DERIVATIVES USEFUL AS ANDROGEN ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-11-23 | — | — | EP | claimed |
| WO-2004072043-A1 | BENZYL UREA AND THIOUREA DERIVATIVES USEFUL AS ANDROGEN ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-26 | — | — | WO | claimed |
| US-7115745-B2 | Benzyl urea and thiourea derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-10-03 | — | — | US | disclosed |
| EP-1597233-A1 | BENZYL UREA AND THIOUREA DERIVATIVES USEFUL AS ANDROGEN ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20050107427-A1 | Benzyl urea and thiourea derivatives | DU DANIEL Y (US) | 2005-05-19 | — | — | US | disclosed |
| WO-2004072043-A1 | BENZYL UREA AND THIOUREA DERIVATIVES USEFUL AS ANDROGEN ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107427-A1 | Benzyl urea and thiourea derivatives | BRDT, TAS2R8, FSHR | ALDH1A1 1968/4885AR 9/4885MEN1 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.