Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782367 | 0.89 | ALDH1A1 (0.60) | MAPTHTTNPC1MAPK1LMNA | |
| SCHEMBL12909297 | 0.88 | MAPT (0.42) | MAPTHTTNPC1MAPK1F2 | |
| SCHEMBL1584825 | 0.87 | F2 (0.59) | MAPTHTTNPC1MAPK1F2 | |
| SCHEMBL14099187 | 0.86 | LMNA (0.50) | MAPTHTTNPC1MAPK1F2 | |
| SCHEMBL10175303 | 0.84 | HTT (0.59) | MAPTHTTNPC1MAPK1LMNA | |
| SCHEMBL18196076 | 0.83 | LMNA (0.50) | MAPTHTTNPC1MAPK1F2 | |
| SCHEMBL20157554 | 0.83 | MAPT (0.54) | MAPTHTTNPC1MAPK1F2 | |
| SCHEMBL10357783 | 0.83 | PTGS1 (0.45) | MAPTHTTF2PLAUELANE | |
| SCHEMBL5382884 | 0.83 | MAPT (0.71) | MAPTHTTNPC1MAPK1LMNA | |
| SCHEMBL17193970 | 0.83 | MAPT (0.54) | MAPTHTTNPC1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154610-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF | JSR CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140154610-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF | JSR CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738194-A1 | AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND APPLICATION THEREOF | JSR Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-7868124-B2 | Polyphenylene-type polymers, preparation method thereof, membranes and fuel cell device comprising said membranes | COMMISSARIAT A L'ENGERGIE ATOMIQUE (FR) | 2011-01-11 | — | — | US | disclosed |
| US-7119215-B2 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2006-10-10 | — | — | US | disclosed |
| US-6946564-B2 | Production method of an intermediate for citalopram | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040230066-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-20040138497-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1125907-B1 | Intermediates for the production of citalopram | SUMIKA FINE CHEMICALS CO LTD (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1428813-A1 | Production method of citalopram and intermediates therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6458975-B1 | 1-(ALPHA-HYDROXY-P-FLUOROBENZYL)-2,4-DIMETHYLBENZENE INTERMEDIATE; PRODUCTION OF 4-(P-FLUOROBENZOYL)ISOPHTHALIC ACID AND USE AS INTERMEDIATE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-10-01 | — | — | US | disclosed |
| US-6433196-B1 | REACTING 3-(DIMETHYLAMINO)PROPYL CHLORIDE IN PRESENCE OF 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND, OR TETRAMETHYLETHYLENEDIAMINE; REDUCTION, CYCLIZATION; ANTIDEPRESSANTS | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-08-13 | — | — | US | disclosed |
| US-20020095051-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-07-18 | — | — | US | disclosed |
| US-20020062040-A1 | PRODUCTION METHOD OF CITALOPRAM, INTERMMEDIATE THEREFOR AND PRODUCTION METHOD OF THE INTERMEDIATE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| EP-1125907-A2 | Intermediates for the production of citalopram | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0101760-B1 | PROCESS FOR PRODUCING FLUOROBENZOPHENONE DERIVATIVES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-02-12 | — | — | EP | disclosed |
| US-4453009-A | HALOGEN-FLUORINE EXCHANGE BETWEEN CORRESPONDING 4-HALOGENO- OR 4,4-DIHALOGENOBENZOPHENONE AND ALKALI FLUORIDE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0101760-A1 | Process for producing fluorobenzophenone derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095051-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | INMT, FAR1, CYP51A1 | MAPT 980/4885HTT 1712/4885NPC1 1350/4885 |
| US-20040138497-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | INMT, FAR1, CYP51A1 | MAPT 980/4885HTT 1712/4885NPC1 1350/4885 |
| US-20020062040-A1 | PRODUCTION METHOD OF CITALOPRAM, INTERMMEDIATE THEREFOR AND PRODUCTION METHOD OF THE INTERMEDIATE | INMT, IMPDH1, HSD17B11 | MAPT 1455/4885HTT 1491/4885NPC1 1610/4885 |
| US-20040230066-A1 | Production method of citalopram, intermediate therefor and production method of the intermediate | INMT, FAR1, CYP51A1 | MAPT 980/4885HTT 1712/4885NPC1 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.