Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | CCKAR | P32238 | 16/20 | 0.53 |
| ▸ | CCKBR | P32239 | 16/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926475 | 0.90 | ACLY (0.53) | ACLYCCKARCCKBRITGB1ITGA4 | |
| SCHEMBL5926865 | 0.87 | ACLY (0.52) | ACLYCCKARCCKBRITGB1ITGA4 | |
| SCHEMBL5927388 | 0.84 | MMP2 (0.60) | CCKARCCKBRITGB1ITGA4 | |
| SCHEMBL8340240 | 0.83 | KCNA5 (0.60) | CCKARCCKBRITGB1ITGA4 | |
| SCHEMBL5926755 | 0.83 | KCNA5 (0.60) | CCKARCCKBRITGB1ITGA4 | |
| SCHEMBL5927344 | 0.82 | ITGB2 (0.62) | ITGB1ITGA4CA1CA2 | |
| SCHEMBL5926727 | 0.81 | MMP2 (0.52) | CCKARCCKBRITGB1ITGA4 | |
| SCHEMBL5926535 | 0.81 | ACLY (0.50) | ACLYCCKARCCKBR | |
| SCHEMBL8337571 | 0.81 | ACLY (0.49) | ACLYCCKARCCKBRITGB1ITGA4 | |
| SCHEMBL4000600 | 0.81 | ALDH1A1 (0.53) | CCKARCCKBRITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |