Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 9/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609800 | 1.00 | GPR119 (0.36) | GPR119NTRK1NR1H2USP30F2R | |
| SCHEMBL609508 | 0.91 | GPR119 (0.39) | GPR119NR1H2 | |
| SCHEMBL612683 | 0.87 | GPR119 (0.36) | GPR119NTRK1TRPV3 | |
| SCHEMBL612843 | 0.87 | GPR119 (0.35) | GPR119NTRK1NR1H2F2RTRPV3 | |
| SCHEMBL611867 | 0.87 | GPR119 (0.35) | GPR119NTRK1 | |
| SCHEMBL611613 | 0.87 | GPR119 (0.35) | GPR119NTRK1 | |
| SCHEMBL611612 | 0.87 | GPR119 (0.35) | GPR119NTRK1 | |
| SCHEMBL612552 | 0.85 | GPR119 (0.37) | GPR119NTRK1TRPV3 | |
| SCHEMBL612289 | 0.84 | GPR119 (0.43) | GPR119NTRK1NR1H2F2R | |
| SCHEMBL13186630 | 0.83 | GPR119 (0.37) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040953-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, GPR132, FFAR2 | GPR119 1/4885NTRK1 3765/4885NR1H2 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.