Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719417 | 0.92 | TAAR1 (0.39) | TAAR1ESR2SLC6A4DHODHPGR | |
| SCHEMBL8124330 | 0.85 | LTA4H (0.41) | ESR2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1535885 | 0.82 | LTA4H (0.44) | KDM4EMAPTHPGDMAOAMAOB | |
| SCHEMBL1532138 | 0.79 | SLC6A4 (0.39) | SLC6A4HTR1ASLC6A2SLC6A3PPARG | |
| SCHEMBL7700101 | 0.79 | GSTP1 (0.46) | FFAR4FFAR1MAOAMAOB | |
| SCHEMBL28013409 | 0.79 | LTA4H (0.41) | SLC6A4DHODHKDM4EMAPTFFAR4 | |
| SCHEMBL6100312 | 0.78 | EGFR (0.41) | ESR2SLC6A4MAPTMAOB | |
| SCHEMBL27709479 | 0.78 | SLC6A4 (0.38) | SLC6A4HTR1ASLC6A2SLC6A3PPARG | |
| SCHEMBL28609139 | 0.77 | ALDH1A1 (0.39) | PPARGPPARAALDH1A1MAPTHPGD | |
| SCHEMBL16719791 | 0.77 | HSD17B1 (0.45) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | claimed |