Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098781 | 1.00 | CYP4F2 (0.47) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL9255724 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL11643306 | 0.81 | CHRNB4 (0.48) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL7483826 | 0.80 | CYP4F2 (0.51) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL3610242 | 0.80 | CYP4F2 (0.51) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL7483813 | 0.80 | CYP4F2 (0.51) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL7490164 | 0.80 | CYP4F2 (0.51) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL1519333 | 0.78 | CYP4F2 (0.50) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL6099549 | 0.77 | NPC1 (0.52) | CYP4F2CYP4A11L3MBTL1GAALMNA | |
| SCHEMBL6099544 | 0.77 | NPC1 (0.52) | CYP4F2CYP4A11L3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022732-B2 | 6-substituted 2,3-dihydro-1,4-benzodioxine, 2-position substituted with carboxy, or (C1 C6)alkoxycarbonyl; diabetes, obesity; 6-[2-(R)-[2-(S)-hydroxy-3-(4-hydroxy-3-methanesulfonamido-phenoxy)propylamino]propyl]-2,3-dihydro-1,4-benzodioxine-2-(R)-carboxylic acid; B3 andrenergic receptor agonist | NISSHIN PHARMA INC. (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20040235921-A1 | Propanolamine derivative having 1, 4-Benzodioxane ring | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1426370-A1 | PROPANOLAMINE DERIVATIVE HAVING 1,4 BENZODIOXANE RING | Nisshin Pharma Inc. (JP) | 2004-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235921-A1 | Propanolamine derivative having 1, 4-Benzodioxane ring | ADRA1D, ADRA1A, ADRB1 | CYP4F2 1929/4885CYP4A11 238/4885L3MBTL1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.