Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703668 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HIF1AHTTTDP1TSHR | |
| SCHEMBL13101021 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HIF1ATDP1TSHRLMNA | |
| SCHEMBL30309507 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HIF1ATDP1TSHRLMNA | |
| SCHEMBL15076678 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HIF1ATDP1TSHRLMNA | |
| SCHEMBL4405560 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HIF1AHTTTDP1LMNA | |
| SCHEMBL10777346 | 0.78 | GAA (0.45) | ALDH1A1HIF1AHTTTDP1TSHR | |
| SCHEMBL27889278 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HIF1ATDP1TSHRLMNA | |
| SCHEMBL10348545 | 0.77 | HTT (0.44) | ALDH1A1HTTTDP1TSHRLMNA | |
| SCHEMBL8416497 | 0.77 | GPR35 (0.51) | ALDH1A1HIF1AHTTTDP1TSHR | |
| SCHEMBL25269818 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HIF1AHTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7002020-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050004174-A1 | Antibacterial agents | GORDEEV MIKHAIL F (US) | 2005-01-06 | — | — | US | disclosed |
| US-6562844-B2 | Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-6531470-B1 | Antimicrobial compounds | PHARMACIA & UPJOHN COMPANY | 2003-03-11 | — | — | US | disclosed |
| US-20020183371-A1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | GORDEEV MIKHAIL F (US) | 2002-12-05 | — | — | US | disclosed |
| US-6239152-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | disclosed |
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183371-A1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PAICS, CDK4, OXA1L | ALDH1A1 1371/4885HIF1A 3384/4885HTT 3776/4885 |
| US-20050004174-A1 | Antibacterial agents | PAICS, OXA1L, PNKP | ALDH1A1 1632/4885HIF1A 3231/4885HTT 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.