Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099363 | 0.88 | KDM4E (0.34) | ALDH1A1KDM4EHPGDRAB9AMEN1 | |
| SCHEMBL30414713 | 0.76 | L3MBTL1 (0.52) | ALDH1A1KDM4EHPGDRAB9AMEN1 | |
| SCHEMBL5334625 | 0.76 | L3MBTL1 (0.52) | ALDH1A1KDM4EHPGDRAB9AMEN1 | |
| SCHEMBL3312778 | 0.67 | HRH1 (0.52) | ALDH1A1MAPTALOX15MBOAT4TDP1 | |
| SCHEMBL5339851 | 0.65 | KDM4E (0.39) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL5332563 | 0.65 | KDM4E (0.45) | ALDH1A1KDM4EHPGDRAB9AMEN1 | |
| SCHEMBL5339446 | 0.65 | L3MBTL1 (0.49) | ALDH1A1KDM4EHPGDRAB9AMEN1 | |
| SCHEMBL16156465 | 0.64 | KDM4E (0.43) | ALDH1A1KDM4EHPGDRAB9AMAPT | |
| SCHEMBL5832250 | 0.64 | NPC1 (0.62) | ALDH1A1KDM4EHPGDRAB9AMAPT | |
| SCHEMBL3310900 | 0.63 | HRH1 (0.50) | ALDH1A1MAPTALOX15MBOAT4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |