Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 9/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099061 | 0.98 | KIFC1 (0.51) | MMEPPARGPPARAKIFC1ITGA4 | |
| SCHEMBL4823685 | 0.89 | CDK2 (0.46) | MMEPPARGPPARACDK2 | |
| SCHEMBL4823689 | 0.89 | CDK2 (0.46) | MMEPPARGPPARACDK2 | |
| SCHEMBL4825751 | 0.88 | CDK2 (0.48) | MMEPPARGPPARAKIFC1CDK2 | |
| SCHEMBL4825747 | 0.88 | CDK2 (0.48) | MMEPPARGPPARAKIFC1CDK2 | |
| SCHEMBL5927352 | 0.84 | KIFC1 (0.61) | MMEKIFC1ITGA4ITGB1ITGB7 | |
| SCHEMBL4829625 | 0.82 | CDK2 (0.55) | KIFC1ITGA4ITGB1ITGB7CDK2 | |
| SCHEMBL4829612 | 0.82 | CDK2 (0.55) | KIFC1ITGA4ITGB1ITGB7CDK2 | |
| SCHEMBL6098431 | 0.82 | KIFC1 (0.69) | MMEPPARGKIFC1ITGA4ITGB1 | |
| SCHEMBL6099348 | 0.81 | MMP12 (0.50) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |