Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 5/20 | 0.50 |
| ▸ | CTSA | P10619 | 11/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099065 | 0.97 | CTSA (0.49) | MMP12CTSAMMECYP26A1MMP3 | |
| SCHEMBL5926401 | 0.89 | CTSA (0.45) | MMP12CTSAMMEFFAR4 | |
| SCHEMBL5926570 | 0.87 | TACR3 (0.48) | MMP12CTSAMME | |
| SCHEMBL6099049 | 0.83 | CTSA (0.50) | MMP12CTSACYP26A1MMP3MMP9 | |
| SCHEMBL5926790 | 0.81 | CTSA (0.43) | MMP12CTSA | |
| SCHEMBL6099342 | 0.81 | MME (0.50) | MME | |
| SCHEMBL6098436 | 0.81 | CTSA (0.51) | MMP12CTSAMMECYP26A1 | |
| SCHEMBL6097852 | 0.80 | CTSA (0.52) | MMP12CTSAMME | |
| SCHEMBL6098336 | 0.79 | MMP12 (0.60) | MMP12CTSAMMECYP26A1MMP13 | |
| SCHEMBL6099061 | 0.79 | KIFC1 (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |