Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.52 |
| ▸ | KIFC1 | Q9BW19 | 3/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927329 | 0.97 | PTPN1 (0.52) | GPR132KIFC1ITGB1ITGA4FPR2 | |
| SCHEMBL28756787 | 0.96 | GPR132 (0.54) | GPR132KIFC1ITGB1ITGA4L3MBTL1 | |
| SCHEMBL5927551 | 0.96 | GPR132 (0.54) | GPR132KIFC1ITGB1ITGA4L3MBTL1 | |
| SCHEMBL5927180 | 0.91 | GPR132 (0.53) | GPR132KIFC1ITGB1ITGA4FPR2 | |
| SCHEMBL5926493 | 0.86 | PTPN1 (0.62) | GPR132KIFC1ITGB1ITGA4L3MBTL1 | |
| SCHEMBL3991795 | 0.86 | PTPN1 (0.62) | GPR132KIFC1ITGB1ITGA4L3MBTL1 | |
| SCHEMBL5927540 | 0.85 | GPR132 (0.56) | GPR132KIFC1L3MBTL1FPR2PTPN1 | |
| SCHEMBL5926983 | 0.85 | LMNA (0.54) | GPR132KIFC1ITGB1ITGA4GPR34 | |
| SCHEMBL5927620 | 0.83 | CA2 (0.63) | GPR132KIFC1L3MBTL1FPR2PTPN1 | |
| SCHEMBL5927385 | 0.83 | CA2 (0.62) | GPR132KIFC1ITGB1ITGA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |