Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101966 | 0.70 | MAPK14 (0.40) | RAB9ASMN1; SMN2KDRGCGRMAPK14 | |
| SCHEMBL6101192 | 0.70 | MAPK14 (0.40) | RAB9ASMN1; SMN2KDRGCGRMAPK14 | |
| SCHEMBL4798689 | 0.68 | RAB9A (0.50) | NPC1MAPTRAB9ASMN1; SMN2KDR | |
| SCHEMBL23858869 | 0.67 | CHEK1 (0.43) | NPC1MAPTRAB9ASMN1; SMN2KDR | |
| SCHEMBL6102380 | 0.66 | MAPK14 (0.57) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4474749 | 0.66 | LTK (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDR | |
| SCHEMBL4487962 | 0.66 | LTK (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDR | |
| SCHEMBL30978979 | 0.65 | KMO (0.40) | PDE1APDE1BPDE3BPDE1CPDE3A | |
| SCHEMBL4806075 | 0.63 | MAPK14 (0.46) | NPC1MAPTRAB9ASMN1; SMN2GCGR | |
| SCHEMBL4802594 | 0.62 | RAB9A (0.41) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287342-A1 | Triazolopyrimidine heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287342-A1 | Triazolopyrimidine heterocycles as cannabinoid receptor modulators | CNR1, CNR2, GPR18 | NPC1 1124/4885MAPT 2586/4885RAB9A 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.