Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24371124 | 0.84 | GAA (0.67) | GAAALDH1A1GFERNPC1SLC7A5 | |
| SCHEMBL27649299 | 0.82 | HSD17B1 (0.51) | GAAALDH1A1GFERCYP4F2CYP4A11 | |
| SCHEMBL30565426 | 0.80 | ALDH1A1 (0.75) | GAAALDH1A1GFERNPC1SLC7A5 | |
| SCHEMBL7237331 | 0.80 | ALDH1A1 (0.75) | GAAALDH1A1GFERNPC1SLC7A5 | |
| SCHEMBL5734658 | 0.80 | ALDH1A1 (0.69) | GAAALDH1A1GFERNPC1SLC7A5 | |
| SCHEMBL13675016 | 0.80 | NPC1 (0.50) | NPC1ERAP2LNPEPMAPTHDAC1 | |
| SCHEMBL8237704 | 0.79 | SMN1; SMN2 (0.48) | GAAALDH1A1GFERNPC1CYP4F2 | |
| SCHEMBL21310771 | 0.78 | GAA (0.58) | GAAALDH1A1GFERNPC1SLC7A5 | |
| SCHEMBL20045098 | 0.78 | ALDH1A1 (0.71) | GAAALDH1A1GFERNPC1SLC7A5 | |
| SCHEMBL8147823 | 0.78 | ALDH1A1 (0.71) | GAAALDH1A1GFERNPC1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112553-B1 | Pesticidal indazole or benzotriazole derivatives | SYNGENTA LIMITED (GB) | 2006-09-26 | — | — | US | disclosed |
| EP-1171437-B1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LTD (GB) | 2003-10-08 | — | — | EP | disclosed |
| EP-1171437-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | Syngenta Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063207-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LIMITED (GB) | 2000-10-26 | — | — | WO | disclosed |