SCHEMBL610026

SCHEMBL610026

O=c1cccc(Cl)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5393702 0.72
SCHEMBL8535240 0.71 NOTUM (0.68)
SCHEMBL5674033 0.67 NOTUM (0.67)
SCHEMBL38665365 0.67
SCHEMBL2030549 0.67
SCHEMBL8246393 0.67
SCHEMBL218183 0.67
SCHEMBL227129 0.67
SCHEMBL1843023 0.67
SCHEMBL595653 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4302831-A1 PROCESS FOR SYNTHESIS OF TIRBANIBULIN Trifarma S.p.A. (IT) 2024-01-10 EP claimed
EP-0124657-B1 METHOD FOR THE PREPARATION OF 3,5,6-TRICHLORO-1H-PYRIDIN-2-ONE RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1987-03-11 EP claimed
US-4546190-A Method for producing 3,5,6-trichloro-1H-pyridine-2-on RUTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-10-08 US claimed
EP-0124657-A1 Method for the preparation of 3,5,6-trichloro-1H-pyridin-2-one RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-11-14 EP claimed
US-4209467-A COBALT COMPLEX CATALYST DAICEL LTD. (JP) 1980-06-24 US claimed
JP-57192368-A None JP disclosed
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 EP disclosed
WO-2025104032-A1 NOVEL CARBOXAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-05-22 WO disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
EP-4058445-B1 GLP-1 RECEPTOR AGONIST AND USE THEREOF ILDONG PHARMACEUTICAL CO LTD (KR) 2025-03-26 EP disclosed
EP-4219460-B1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA INC (US) 2025-02-26 EP disclosed
EP-0393861-A1 Fungicides ZENECA LIMITED (GB) 1990-10-24 EP disclosed
EP-0124657-B1 METHOD FOR THE PREPARATION OF 3,5,6-TRICHLORO-1H-PYRIDIN-2-ONE RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1987-03-11 EP disclosed
US-4546190-A Method for producing 3,5,6-trichloro-1H-pyridine-2-on RUTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-10-08 US disclosed
US-4546190-A Method for producing 3,5,6-trichloro-1H-pyridine-2-on RUTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-10-08 US disclosed
EP-0124657-A1 Method for the preparation of 3,5,6-trichloro-1H-pyridin-2-one RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-11-14 EP disclosed
EP-0124657-A1 Method for the preparation of 3,5,6-trichloro-1H-pyridin-2-one RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-11-14 EP disclosed
JP-S57192368-A 1,2-DIHYDROCYCLOBUTA(B)PYRIDINE-4(3H)-ONES SEITETSU KAGAKU CO LTD 1982-11-26 JP disclosed
US-4209467-A COBALT COMPLEX CATALYST DAICEL LTD. (JP) 1980-06-24 US disclosed