Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27571208 | 1.00 | ACHE (0.42) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL1201070 | 0.98 | ACHE (0.41) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL25422694 | 0.98 | ACHE (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| SCHEMBL33607 | 0.98 | ACHE (0.43) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL28176347 | 0.96 | ACHE (0.39) | ACHEAPEX1NPSR1KDM4EMAPK1 | |
| Bromide SCHEMBL718176 | 0.96 | ACHE (0.42) | ACHEAPEX1KDM4EMAPK1HIF1A | |
| Fluoride Ion SCHEMBL8578974 | 0.96 | ACHE (0.42) | ACHEAPEX1KDM4EMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL21827668 | 0.96 | ACHE (0.42) | ACHEAPEX1KDM4EMAPK1HIF1A | |
| Iodide SCHEMBL23607568 | 0.96 | ACHE (0.42) | ACHEAPEX1KDM4EMAPK1HIF1A | |
| SCHEMBL28096783 | 0.96 | ACHE (0.42) | ACHEAPEX1KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 14210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080300-A | Preparation method of electrochromic gel | — | 2026-05-26 | — | — | CN | claimed |
| CN-122071561-A | Drilling fluid adhesion promoter and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-122060110-A | Polymerizable organic-inorganic hybrid flexible gel scintillator material and preparation method and application thereof | 福州大学 | 2026-05-19 | — | — | CN | claimed |
| CN-116925280-B | Preparation method of waterproof amphoteric acrylic retanning fatliquor | 四川大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122070397-A | Use of fast reverse cationic emulsion polymers with polyvinylamines as retention and drainage aids | 凯米拉公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037093-A | Plugging agent for shale, and preparation method and application thereof | 中国地质大学（北京） | 2026-05-15 | — | — | CN | claimed |
| CN-122039489-A | Polyelectrolyte complex for constructing papermaking filler reinforcement and papermaking method | 银泉(佛山)新材料有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4739418-A2 | ONE-PASS DEOXYGENATION METHOD FOR POLYACRYLAMIDE PRODUCTION | KEMIRA OYJ (FI) | 2026-05-13 | — | — | EP | claimed |
| CN-122028892-A | Composition for conditioning hair | 莱雅公司 | 2026-05-12 | — | — | CN | claimed |
| US-12624308-B2 | Biodegradable delivery particles | ENCAPSYS, LLC (US) | 2026-05-12 | — | — | US | claimed |
| US-4217262-A | Preparation of a cationic copolymer | AMERICAN CYANAMID COMPANY (US) | 1980-08-12 | — | — | US | claimed |
| EP-0007259-A1 | Method of resolving oil-in-water emulsions | CALGON CORPORATION (US) | 1980-01-23 | — | — | EP | claimed |
| US-4171418-A | WATER-SOLUBLR ACRYLAMIDE COPOLYMERS CONTAINING HYDROPHOBIC AND IONIC UNITS | AMERICAN CYANAMID COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4160742-A | USING AS DEEMULSIFIER A COPOLYMER OF ACRYLAMIDE AND METHYLACRYLAMIDOTRIMETHYLAMMONIUM CHLORIDE | CALGON CORPORATION (US) | 1979-07-10 | — | — | US | claimed |
| US-4152200-A | CATIONIC POLYMERS, WATER IN OIL EMULSIONS | AMERICAN CYANAMID COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4148639-A | Water-insensitive electroconductive polymers | CALGON CORPORATION (US) | 1979-04-10 | — | — | US | claimed |
| US-4131576-A | Process for the preparation of graft copolymers of a water soluble monomer and polysaccharide employing a two-phase reaction system | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1978-12-26 | — | — | US | claimed |
| US-4022731-A | ACRYLAMIDE, OIL, EMULSIFYING AGENT | AMERICAN CYANAMID COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| US-3943996-A | Low fluid loss cementing compositions | CALGON CORPORATION (US) | 1976-03-16 | — | — | US | claimed |
| US-3931096-A | METHACRYLAMIDOPROPYL TRIMETHYLAMMONIUM CHLORIDE POLYMER | CALGON CORPORATION (US) | 1976-01-06 | — | — | US | claimed |