Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 16/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102056 | 0.86 | KCNN4 (0.51) | CHRM5FEN1 | |
| SCHEMBL6100789 | 0.83 | CMA1 (0.53) | CHRM5 | |
| SCHEMBL4150996 | 0.81 | CYP1A2 (0.51) | — | |
| SCHEMBL6100796 | 0.81 | PTPN1 (0.42) | CHRM5FEN1 | |
| SCHEMBL5766292 | 0.80 | CA12 (0.41) | — | |
| SCHEMBL6099606 | 0.79 | GAA (0.41) | — | |
| SCHEMBL6101383 | 0.79 | CA1 (0.40) | — | |
| SCHEMBL6102631 | 0.79 | CHRM5 (0.41) | CHRM5 | |
| SCHEMBL6099694 | 0.78 | CYP1B1 (0.41) | FEN1 | |
| SCHEMBL5793964 | 0.76 | FAAH (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | VERSCHUEREN GASTON W | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | SULT1A1, SULT2A1, SULT1E1 | CHRM5 782/4885FEN1 531/4885PIM1 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.