Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.37 |
| ▸ | PKM | P14618 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101224 | 0.88 | CASP3 (0.42) | MAPTALDH1A1PKMPOLBSMN1; SMN2 | |
| SCHEMBL4142509 | 0.83 | KDM4E (0.43) | MAPTALDH1A1PKMPOLBCYP2C19 | |
| SCHEMBL6100747 | 0.76 | TYR (0.37) | MAPTALDH1A1PKMPOLBKMT2A | |
| SCHEMBL6100137 | 0.72 | KDM4E (0.48) | MAPTALDH1A1PKMPOLBSMN1; SMN2 | |
| SCHEMBL13943354 | 0.72 | CYP1A2 (0.43) | MAPTALDH1A1PKMPOLBCYP3A4 | |
| SCHEMBL4150453 | 0.71 | CYP1A2 (0.54) | MAPTALDH1A1SMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL6102521 | 0.70 | KCNN4 (0.39) | POLBSMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL6101774 | 0.70 | TSHR (0.51) | MAPTALDH1A1PKMSMN1; SMN2MAPK1 | |
| SCHEMBL6101250 | 0.69 | CASP3 (0.48) | MAPTALDH1A1PKMPOLBSMN1; SMN2 | |
| SCHEMBL4150996 | 0.69 | CYP1A2 (0.51) | ALDH1A1POLBCYP2C19HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | VERSCHUEREN GASTON W | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | SULT1A1, SULT2A1, SULT1E1 | MAPT 4622/4885ALDH1A1 1124/4885PKM 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.