SCHEMBL610118

SCHEMBL610118

CCN(CC)CSC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.37
CHRM4 P08173 3/20 0.37
CHRM1 P11229 3/20 0.37
CHRM3 P20309 3/20 0.37
CHRM5 P08912 2/20 0.37
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.34
BLM P54132 1/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
PAOX Q6QHF9 1/20 0.31
TRPA1 O75762 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10582483 0.75 MAPT (0.47) CHRM2CHRM4CHRM1CHRM3CHRM5
SCHEMBL610847 0.75
SCHEMBL764245 0.74
SCHEMBL619142 0.72 ALDH1A1 (0.34) CYP2C19POLBBLMATMALDH1A1
SCHEMBL24587745 0.72 PAOX (0.42) CHRM2CHRM4CHRM1CHRM3CHRM5
SCHEMBL20679744 0.71
Acetone SCHEMBL3715272 0.70 LMNA (0.46) CHRM2CHRM4CHRM1CHRM3CHRM5
Acetic Acid SCHEMBL22152 0.67 FFAR3 (0.50) CHRM2CHRM4CHRM1CHRM3CHRM5
Acetone SCHEMBL11644767 0.67 CHRM2 (0.44) CHRM2CHRM4CHRM1CHRM3CHRM5
Acetic Acid SCHEMBL16244302 0.67 FFAR3 (0.50) CHRM2CHRM4CHRM1CHRM3CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed