Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102882 | 0.92 | CA12 (0.40) | TP53ALDH1A1CA12CA1CA2 | |
| SCHEMBL6101799 | 0.86 | MMP8 (0.46) | TP53ALDH1A1MMP8NPY1RNPY2R | |
| SCHEMBL6102207 | 0.80 | CYP1A2 (0.43) | TP53ALDH1A1MMP8NPY1RNPY2R | |
| SCHEMBL4823221 | 0.78 | CYP3A4 (0.38) | TP53ALDH1A1TACR1MAPTKDM4E | |
| SCHEMBL6102568 | 0.76 | NPC1 (0.44) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL4824656 | 0.75 | ELANE (0.48) | HPRT1TACR1PPARGMAPTELANE | |
| SCHEMBL6102003 | 0.73 | PPID (0.38) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL5930675 | 0.72 | CA12 (0.39) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL6099637 | 0.72 | CYP2C9 (0.44) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL5930595 | 0.71 | L3MBTL1 (0.39) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | KRT18, CDC73, DSG1 | TP53 375/4885ALDH1A1 1148/4885MMP8 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.