Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20490501 | 0.81 | HDAC4 (0.66) | PTPN11CTSDHDAC3HDAC4HDAC1 | |
| SCHEMBL741751 | 0.80 | MEN1 (0.58) | MEN1KMT2ACTSDTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8550499 | 0.78 | MEN1 (0.56) | MEN1KMT2ACTSDTDP1L3MBTL1 | |
| SCHEMBL6098736 | 0.77 | RXRA (0.47) | MEN1KMT2ACTSDTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL30467539 | 0.76 | APP (0.52) | NPC1RAB9AFFAR1CTSDAPP | |
| SCHEMBL17450483 | 0.74 | APP (0.50) | PTPN11CA12CA1CA2CA9 | |
| Acetic Acid SCHEMBL9853044 | 0.74 | MEN1 (0.53) | MEN1KMT2ACTSDTDP1L3MBTL1 | |
| SCHEMBL5806814 | 0.74 | NPC1 (0.43) | NPC1RAB9AFFAR1CTSDAPP | |
| SCHEMBL4543120 | 0.73 | CYP2D6 (0.47) | PTPN11CA12CA1CA2CA9 | |
| SCHEMBL6100230 | 0.73 | EPHX1 (0.49) | MEN1KMT2AFFAR1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |