Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494261 | 0.83 | EPHX1 (0.45) | EPHX1KMT2AMEN1FFAR1 | |
| SCHEMBL741751 | 0.80 | MEN1 (0.58) | EPHX1KMT2AMEN1CTSD | |
| Hydrochloric Acid SCHEMBL8550499 | 0.78 | MEN1 (0.56) | EPHX1KMT2AMEN1CTSD | |
| SCHEMBL14797023 | 0.78 | CYSLTR2 (0.55) | EPHX1CYSLTR2CYSLTR1CNR1MAOA | |
| SCHEMBL6098736 | 0.77 | RXRA (0.47) | EPHX1MAOAKMT2AMEN1CTSD | |
| SCHEMBL8410311 | 0.75 | ITGB3 (0.55) | CYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL30802684 | 0.74 | HTR3E (0.46) | KMT2AMEN1 | |
| Acetic Acid SCHEMBL9853044 | 0.74 | MEN1 (0.53) | EPHX1KMT2AMEN1CTSD | |
| SCHEMBL6101862 | 0.73 | PTPN11 (0.44) | KMT2AMEN1FFAR1CTSD | |
| SCHEMBL27854366 | 0.73 | PTGS1 (0.59) | MAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |