Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PDE5A | O76074 | 3/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102401 | 0.87 | TSHR (0.47) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5793864 | 0.83 | PDE5A (0.49) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4158476 | 0.81 | KDM4E (0.46) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6099895 | 0.81 | MEN1 (0.45) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5768586 | 0.80 | HPGD (0.58) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6099645 | 0.77 | HPGD (0.60) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5794622 | 0.77 | TSHR (0.54) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6099226 | 0.76 | CMA1 (0.58) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6101296 | 0.75 | PKM (0.47) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6101379 | 0.75 | TSHR (0.51) | TSHRPKMKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | VERSCHUEREN GASTON W | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | SULT1A1, SULT2A1, SULT1E1 | TSHR 3033/4885PKM 2808/4885KMT2A 1121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.